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Di-n-Butyl Phthalate and Its Monoester Metabolite Impairs Steroid Hormone Biosynthesis in Human Cells: Mechanistic In Vitro Studies

The widespread environmental contaminant di-n-butyl phthalate (DBP) has been linked with reduced testosterone levels and adverse reproductive health outcomes in men. However, the underlying mechanisms of these anti-androgenic effects and the potential effects on other classes of steroid hormones rem...

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Detalles Bibliográficos
Autores principales: Källsten, Liselott, Pierozan, Paula, Martin, Jonathan W., Karlsson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561974/
https://www.ncbi.nlm.nih.gov/pubmed/36230992
http://dx.doi.org/10.3390/cells11193029