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The Kinetic Mechanism of 3′-5′ Exonucleolytic Activity of AP Endonuclease Nfo from E. coli

Escherichia coli apurinic/apyrimidinic (AP) endonuclease Nfo is one of the key participants in DNA repair. The principal biological role of this enzyme is the recognition and hydrolysis of AP sites, which arise in DNA either as a result of the spontaneous hydrolysis of an N-glycosidic bond with inta...

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Detalles Bibliográficos
Autores principales: Senchurova, Svetlana I., Kuznetsova, Aleksandra A., Ishchenko, Alexander A., Saparbaev, Murat, Fedorova, Olga S., Kuznetsov, Nikita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562005/
https://www.ncbi.nlm.nih.gov/pubmed/36230958
http://dx.doi.org/10.3390/cells11192998