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The Kinetic Mechanism of 3′-5′ Exonucleolytic Activity of AP Endonuclease Nfo from E. coli
Escherichia coli apurinic/apyrimidinic (AP) endonuclease Nfo is one of the key participants in DNA repair. The principal biological role of this enzyme is the recognition and hydrolysis of AP sites, which arise in DNA either as a result of the spontaneous hydrolysis of an N-glycosidic bond with inta...
Autores principales: | Senchurova, Svetlana I., Kuznetsova, Aleksandra A., Ishchenko, Alexander A., Saparbaev, Murat, Fedorova, Olga S., Kuznetsov, Nikita A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562005/ https://www.ncbi.nlm.nih.gov/pubmed/36230958 http://dx.doi.org/10.3390/cells11192998 |
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