Presynaptic 5-HT(2A)-mGlu2/3 Receptor–Receptor Crosstalk in the Prefrontal Cortex: Metamodulation of Glutamate Exocytosis

The glutamatergic nerve endings of a rat prefrontal cortex (PFc) possess presynaptic 5-HT(2A) heteroreceptors and mGlu2/3 autoreceptors, whose activation inhibits glutamate exocytosis, and is measured as 15 mM KCl-evoked [(3)H]D-aspartate ([(3)H]D-asp) release (which mimics glutamate exocytosis). Th...

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Detalles Bibliográficos
Autores principales: Taddeucci, Alice, Olivero, Guendalina, Roggeri, Alessandra, Milanese, Claudio, Giorgio, Francesco Paolo Di, Grilli, Massimo, Marchi, Mario, Garrone, Beatrice, Pittaluga, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562019/
https://www.ncbi.nlm.nih.gov/pubmed/36230998
http://dx.doi.org/10.3390/cells11193035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562019/
https://www.ncbi.nlm.nih.gov/pubmed/36230998
http://dx.doi.org/10.3390/cells11193035

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