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Presynaptic 5-HT(2A)-mGlu2/3 Receptor–Receptor Crosstalk in the Prefrontal Cortex: Metamodulation of Glutamate Exocytosis
The glutamatergic nerve endings of a rat prefrontal cortex (PFc) possess presynaptic 5-HT(2A) heteroreceptors and mGlu2/3 autoreceptors, whose activation inhibits glutamate exocytosis, and is measured as 15 mM KCl-evoked [(3)H]D-aspartate ([(3)H]D-asp) release (which mimics glutamate exocytosis). Th...
Autores principales: | Taddeucci, Alice, Olivero, Guendalina, Roggeri, Alessandra, Milanese, Claudio, Giorgio, Francesco Paolo Di, Grilli, Massimo, Marchi, Mario, Garrone, Beatrice, Pittaluga, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562019/ https://www.ncbi.nlm.nih.gov/pubmed/36230998 http://dx.doi.org/10.3390/cells11193035 |
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