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The Neuroprotective Effects of mGlu1 Receptor Antagonists Are Mediated by an Enhancement of GABAergic Synaptic Transmission via a Presynaptic CB1 Receptor Mechanism

In this study, we investigated the cross-talk between mGlu1 and CB1 receptors in modulating GABA hippocampal output in whole-cell voltage clamp recordings in rat hippocampal acute slices, in organotypic hippocampal slices exposed to oxygen and glucose deprivation (OGD) and in gerbils subjected to gl...

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Detalles Bibliográficos
Autores principales: Landucci, Elisa, Berlinguer-Palmini, Rolando, Baccini, Gilda, Boscia, Francesca, Gerace, Elisabetta, Mannaioni, Guido, Pellegrini-Giampietro, Domenico E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562021/
https://www.ncbi.nlm.nih.gov/pubmed/36230976
http://dx.doi.org/10.3390/cells11193015