The entry of unclosed autophagosomes into vacuoles and its physiological relevance

It is widely stated in the literature that closed mature autophagosomes (APs) fuse with lysosomes/vacuoles during macroautophagy/autophagy. Previously, we showed that unclosed APs accumulated as clusters outside vacuoles in Vps21/Rab5 and ESCRT mutants after a short period of nitrogen starvation. Ho...

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Detalles Bibliográficos
Autores principales: Wu, Zulin, Xu, Haiqian, Wang, Pei, Liu, Ling, Cai, Juan, Chen, Yun, Zhao, Xiaomin, You, Xia, Liu, Junze, Guo, Xiangrui, Xie, Tingting, Feng, Jiajie, Zhou, Fan, Li, Rui, Xie, Zhiping, Xue, Yanhong, Fu, Chuanhai, Liang, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562215/
https://www.ncbi.nlm.nih.gov/pubmed/36227834
http://dx.doi.org/10.1371/journal.pgen.1010431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562215/
https://www.ncbi.nlm.nih.gov/pubmed/36227834
http://dx.doi.org/10.1371/journal.pgen.1010431

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