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Spatial Profiling of the Prostate Cancer Tumor Microenvironment Reveals Multiple Differences in Gene Expression and Correlation with Recurrence Risk

SIMPLE SUMMARY: In prostate cancer (PCa), the tumor microenvironment plays a crucial role in both the development and progression of the disease. We used Digital Spatial Profiling multiplex technology to assess the expression of 58 protein and 1825 RNA transcripts in traditionally challenging sample...

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Detalles Bibliográficos
Autores principales: Kumar, Vinay, Randhawa, Pavneet, Bilodeau, Robert, Mercola, Dan, McClelland, Michael, Agrawal, Anshu, Nguyen, James, Castro, Patricia, Ittmann, Michael M., Rahmatpanah, Farah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562240/
https://www.ncbi.nlm.nih.gov/pubmed/36230846
http://dx.doi.org/10.3390/cancers14194923