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Distinct spatial distribution and roles of Kupffer cells and monocyte-derived macrophages in mouse acute liver injury

Macrophages are key regulators of inflammation and repair, but their heterogeneity and multiple roles in the liver are not fully understood. We aimed herein to map the intrahepatic macrophage populations and their function(s) during acute liver injury. We used flow cytometry, gene expression analysi...

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Detalles Bibliográficos
Autores principales: Flores Molina, Manuel, Abdelnabi, Mohamed N., Mazouz, Sabrina, Villafranca-Baughman, Deborah, Trinh, Vincent Quoc-Huy, Muhammad, Shafi, Bédard, Nathalie, Osorio Laverde, David, Hassan, Ghada S., Di Polo, Adriana, Shoukry, Naglaa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562324/
https://www.ncbi.nlm.nih.gov/pubmed/36248843
http://dx.doi.org/10.3389/fimmu.2022.994480