AI protein structure prediction-based modeling and mutagenesis of a protostome receptor and peptide ligands reveal key residues for their interaction

The protostome leucokinin (LK) signaling system, including LK peptides and their G protein-coupled receptors, has been characterized in several species. Despite the progress, molecular mechanisms governing LK peptide–receptor interactions remain to be elucidated. Previously, we identified a precurso...

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Detalles Bibliográficos
Autores principales: Guo, Shi-Qi, Li, Ya-Dong, Chen, Ping, Zhang, Guo, Wang, Hui-Ying, Jiang, Hui-Min, Liu, Wei-Jia, Xu, Ju-Ping, Ding, Xue-Ying, Fu, Ping, Yu, Ke, Zhou, Hai-Bo, Checco, James W., Jing, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562341/
https://www.ncbi.nlm.nih.gov/pubmed/36049520
http://dx.doi.org/10.1016/j.jbc.2022.102440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562341/
https://www.ncbi.nlm.nih.gov/pubmed/36049520
http://dx.doi.org/10.1016/j.jbc.2022.102440

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