Populations of Tau Conformers Drive Prion-like Strain Effects in Alzheimer’s Disease and Related Dementias

Recent findings of diverse populations of prion-like conformers of misfolded tau protein expand the prion concept to Alzheimer’s disease (AD) and monogenic frontotemporal lobar degeneration (FTLD)-MAPT P301L, and suggest that distinct strains of misfolded proteins drive the phenotypes and progressio...

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Detalles Bibliográficos
Autores principales: Hromadkova, Lenka, Siddiqi, Mohammad Khursheed, Liu, He, Safar, Jiri G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562632/
https://www.ncbi.nlm.nih.gov/pubmed/36230957
http://dx.doi.org/10.3390/cells11192997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562632/
https://www.ncbi.nlm.nih.gov/pubmed/36230957
http://dx.doi.org/10.3390/cells11192997

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