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Taraxasterol Inhibits Tumor Growth by Inducing Apoptosis and Modulating the Tumor Microenvironment in Non-Small Cell Lung Cancer

SIMPLE SUMMARY: Taraxasterol (TAX) demonstrates strong pharmacological activity in some diseases. In this study, we demonstrate that TAX induces S-phase cell cycle arrest, prevents cell migration by interfering EMT, and induces cancer cell apoptosis. In addition, TAX administration downregulated the...

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Detalles Bibliográficos
Autores principales: Lu, Junjie, Shuai, Bo, Shou, Zhexing, Guo, Weina, Zhou, Cong, Ouyang, Xiaohu, Zhou, Haifeng, Li, Junyi, Cui, Jing, Jiang, Feng, Jin, Kim Yun, Sarapultsev, Alexey, Li, Fangfei, Zhang, Ge, Luo, Shanshan, Hu, Desheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562636/
https://www.ncbi.nlm.nih.gov/pubmed/36230568
http://dx.doi.org/10.3390/cancers14194645