Locus-Specific Enrichment Analysis of 5-Hydroxymethylcytosine Reveals Novel Genes Associated with Breast Carcinogenesis

HIGHLIGHTS: The conversion of 5-methylcytosine to 5-hydroxymethylcytosine relaxes the repressive marks of gene expression, and their imbalance leads to cancer development. Global loss of 5-hmC is found to be associated with the downregulation of TET1 and TET3 genes in breast cancer. Genome-wide anal...

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Detalles Bibliográficos
Autores principales: Ramasamy, Deepa, Rao, Arunagiri Kuha Deva Magendhra, Balaiah, Meenakumari, Vittal Rangan, Arvinden, Sundersingh, Shirley, Veluswami, Sridevi, Thangarajan, Rajkumar, Mani, Samson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562672/
https://www.ncbi.nlm.nih.gov/pubmed/36230901
http://dx.doi.org/10.3390/cells11192939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562672/
https://www.ncbi.nlm.nih.gov/pubmed/36230901
http://dx.doi.org/10.3390/cells11192939

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