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Functional Downregulation of PD-L1 and PD-L2 by CpG and non-CpG Oligonucleotides in Melanoma Cells

SIMPLE SUMMARY: Although metastatic melanoma is still not a curable disease, targeting of immunologically relevant checkpoints represents a turning point in the treatment. Particularly, targeting the interaction between PD-L1 and its referring receptor PD-1 with antibodies has been shown to activate...

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Detalles Bibliográficos
Autores principales: Kleemann, Johannes, Steinhorst, Katja, König, Veronika, Zöller, Nadja, Cinatl, Jindrich, Özistanbullu, Deniz, Kaufmann, Roland, Meissner, Markus, Kippenberger, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562717/
https://www.ncbi.nlm.nih.gov/pubmed/36230620
http://dx.doi.org/10.3390/cancers14194698