Stable cerebrospinal fluid neurogranin and β-site amyloid precursor protein cleaving enzyme 1 levels differentiate predementia Alzheimer’s disease patients

Cerebrospinal fluid (CSF) β-site amyloid precursor protein cleaving enzyme 1 (BACE1), neurogranin and the neurogranin/BACE1 ratio are proposed markers for Alzheimer’s disease. BACE1 is also a drug target. However, CSF levels may differ between early-stage amyloid plaque formation (A) and later stage...

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Detalles Bibliográficos
Autores principales: Kirsebom, Bjørn Eivind, Richter, Grit, Nordengen, Kaja, Aarsland, Dag, Bråthen, Geir, Tijms, Betty M, Visser, Pieter Jelle, Nilsson, Johanna, Selnes, Per, Kramberger, Milica G, Winblad, Bengt, Waterloo, Knut, Gísladóttir, Berglind, Blennow, Kaj, Fladby, Tormod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562788/
https://www.ncbi.nlm.nih.gov/pubmed/36262371
http://dx.doi.org/10.1093/braincomms/fcac244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562788/
https://www.ncbi.nlm.nih.gov/pubmed/36262371
http://dx.doi.org/10.1093/braincomms/fcac244

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