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HPV16 E7 Nucleotide Variants Found in Cancer-Free Subjects Affect E7 Protein Expression and Transformation

SIMPLE SUMMARY: Human papillomaviruses (HPV) are one of the deadliest viruses causing cancer resulting in over 300,000 deaths annually in the world. HPV16 is the most oncogenic form of HPV and is responsible for over half of all HPV-driven tumors. The viral E7 gene encodes a powerful oncoprotein tha...

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Detalles Bibliográficos
Autores principales: Lou, Hong, Boland, Joseph F., Li, Hongchuan, Burk, Robert, Yeager, Meredith, Anderson, Stephen K., Wentzensen, Nicolas, Schiffman, Mark, Mirabello, Lisa, Dean, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562847/
https://www.ncbi.nlm.nih.gov/pubmed/36230818
http://dx.doi.org/10.3390/cancers14194895