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PGC-1β and ERRα Promote Glutamine Metabolism and Colorectal Cancer Survival via Transcriptional Upregulation of PCK2

SIMPLE SUMMARY: Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 Beta (PGC-1β) and Estrogen-Related Receptor Alpha (ERRα) are proteins that are over-expressed to support the survival of colorectal cancer (CRC) cells, but the details of how they promote the growth of CRC has not been d...

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Detalles Bibliográficos
Autores principales: Frodyma, Danielle E., Troia, Thomas C., Rao, Chaitra, Svoboda, Robert A., Berg, Jordan A., Shinde, Dhananjay D., Thomas, Vinai C., Lewis, Robert E., Fisher, Kurt W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562873/
https://www.ncbi.nlm.nih.gov/pubmed/36230802
http://dx.doi.org/10.3390/cancers14194879