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Hierarchical Clustering and Trajectory Analyses Reveal Viremia-Independent B-Cell Perturbations in HIV-2 Infection

Time to AIDS in HIV-2 infection is approximately twice as long compared to in HIV-1 infection. Despite reduced viremia, HIV-2-infected individuals display signs of chronic immune activation. In HIV-1-infected individuals, B-cell hyperactivation is driven by continuous antigen exposure. However, the...

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Detalles Bibliográficos
Autores principales: Johansson, Emil, Kerkman, Priscilla F., Scharf, Lydia, Lindman, Jacob, Szojka, Zsófia I., Månsson, Fredrik, Biague, Antonio, Medstrand, Patrik, Norrgren, Hans, Buggert, Marcus, Karlsson, Annika C., Forsell, Mattias N. E., Esbjörnsson, Joakim, Jansson, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562922/
https://www.ncbi.nlm.nih.gov/pubmed/36231103
http://dx.doi.org/10.3390/cells11193142