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α-Hemihydrate calcium sulfate/n-hydroxyapatite combined with metformin promotes osteogenesis in vitro and in vivo

This study aimed to examine the effects of loading different concentrations of metformin onto an α-hemihydrate calcium sulfate/nano-hydroxyapatite (α-CSH/nHA) composite. The material characteristics, biocompatibility, and bone formation were compared as functions of the metformin concentration. X-ra...

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Detalles Bibliográficos
Autores principales: Liu, Sirui, Fu, Haojie, Lv, Yan, Jiao, Jing, Guo, Runying, Yang, Yanyu, Dong, Wenhang, Mi, Hongyan, Wang, Meiyue, Liu, Mengzhe, Li, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563001/
https://www.ncbi.nlm.nih.gov/pubmed/36246380
http://dx.doi.org/10.3389/fbioe.2022.899157