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The Adhesion G-Protein-Coupled Receptor GPR115/ADGRF4 Regulates Epidermal Differentiation and Associates with Cytoskeletal KRT1

Among the 33 human adhesion G-protein-coupled receptors (aGPCRs), a unique subfamily of GPCRs, only ADGRF4, encoding GPR115, shows an obvious skin-dominated transcriptomic profile, but its expression and function in skin is largely unknown. Here, we report that GPR115 is present in a small subset of...

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Detalles Bibliográficos
Autores principales: Winkler, Romy, Quaas, Marianne, Glasmacher, Stefan, Wolfrum, Uwe, Thalheim, Torsten, Galle, Jörg, Krohn, Knut, Magin, Thomas M., Aust, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563031/
https://www.ncbi.nlm.nih.gov/pubmed/36231117
http://dx.doi.org/10.3390/cells11193151