TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway

BACKGROUND: Microglia, the innate immune cells in the central nervous system, play an essential role in brain homeostasis, neuroinflammation and brain infections. Dysregulated microglia, on the other hand, are associated with neurodegenerative diseases, yet the mechanisms underlying pro-inflammatory...

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Detalles Bibliográficos
Autores principales: Li, Rong, Zhang, Jing, Wang, Qiong, Cheng, Meng, Lin, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563125/
https://www.ncbi.nlm.nih.gov/pubmed/36241997
http://dx.doi.org/10.1186/s12974-022-02619-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563125/
https://www.ncbi.nlm.nih.gov/pubmed/36241997
http://dx.doi.org/10.1186/s12974-022-02619-3

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