Nuclear Beclin 1 Destabilizes Retinoblastoma Protein to Promote Cell Cycle Progression and Colorectal Cancer Growth

SIMPLE SUMMARY: The role of autophagy core-protein Beclin 1 in colorectal cancer (CRC) development remains controversial. Here, we show that nuclear Beclin 1 is up-regulated in CRC with a negative correlation to RB protein expression. Silencing of BECN1 up-regulates RB expression resulting in cell c...

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Detalles Bibliográficos
Autores principales: Pan, Yang, Zhao, Zhiqiang, Li, Juan, Li, Jinsong, Luo, Yue, Li, Weiyuxin, You, Wanbang, Zhang, Yujun, Li, Zhonghan, Yang, Jian, Xiao, Zhi-Xiong Jim, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563141/
https://www.ncbi.nlm.nih.gov/pubmed/36230664
http://dx.doi.org/10.3390/cancers14194735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563141/
https://www.ncbi.nlm.nih.gov/pubmed/36230664
http://dx.doi.org/10.3390/cancers14194735

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