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Characterization of pyruvate metabolism and citric acid cycle patterns predicts response to immunotherapeutic and ferroptosis in gastric cancer

BACKGROUND: Gastric cancer is one of the most common malignancies of the digestive system with a high lethal rate. Studies have shown that inherited and acquired mutations in pyruvate metabolism and citric acid cycle (P-CA) enzymes are involved in tumorigenesis and tumor development. However, it is...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Xu, Bing, Du, Jing, Xia, Jun, Lei, Guojie, Zhou, Chaoting, Hu, Jiayu, Zhang, Yinhao, Chen, Sufeng, Shao, Fangchun, Yang, Jiyun, Li, Yanchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563156/
https://www.ncbi.nlm.nih.gov/pubmed/36229828
http://dx.doi.org/10.1186/s12935-022-02739-z