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Characterization of pyruvate metabolism and citric acid cycle patterns predicts response to immunotherapeutic and ferroptosis in gastric cancer

BACKGROUND: Gastric cancer is one of the most common malignancies of the digestive system with a high lethal rate. Studies have shown that inherited and acquired mutations in pyruvate metabolism and citric acid cycle (P-CA) enzymes are involved in tumorigenesis and tumor development. However, it is...

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Detalles Bibliográficos
Autores principales:	Wang, Xu, Xu, Bing, Du, Jing, Xia, Jun, Lei, Guojie, Zhou, Chaoting, Hu, Jiayu, Zhang, Yinhao, Chen, Sufeng, Shao, Fangchun, Yang, Jiyun, Li, Yanchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563156/ https://www.ncbi.nlm.nih.gov/pubmed/36229828 http://dx.doi.org/10.1186/s12935-022-02739-z

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