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Exploring DNA methylation within the CYP17A gene as a potential mediator between childhood adversity and stress-related phenotypes in schizophrenia

INTRODUCTION: Stress caused by childhood adversity (CA) is known to contribute to schizophrenia risk and symptoms. Its effects might be mediated by epigenetic mechanisms, specifically DNA methylation (meDNA) within relevant genes, and predominantly influence the hippocampus and prefrontal cortex (PF...

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Detalles Bibliográficos
Autores principales: Alfimova, M., Kondratyev, N., Golov, A., Gabaeva, M., Plakunova, V., Golimbet, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563213/
http://dx.doi.org/10.1192/j.eurpsy.2022.517