Cargando…
Exploring DNA methylation within the CYP17A gene as a potential mediator between childhood adversity and stress-related phenotypes in schizophrenia
INTRODUCTION: Stress caused by childhood adversity (CA) is known to contribute to schizophrenia risk and symptoms. Its effects might be mediated by epigenetic mechanisms, specifically DNA methylation (meDNA) within relevant genes, and predominantly influence the hippocampus and prefrontal cortex (PF...
Autores principales: | Alfimova, M., Kondratyev, N., Golov, A., Gabaeva, M., Plakunova, V., Golimbet, V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563213/ http://dx.doi.org/10.1192/j.eurpsy.2022.517 |
Ejemplares similares
-
A Role of DNA Methylation within the CYP17A1 Gene in the Association of Genetic and Environmental Risk Factors with Stress-Related Manifestations of Schizophrenia
por: Alfimova, Margarita, et al.
Publicado: (2022) -
Profiling haplotype specific CpG and CpH methylation within a schizophrenia GWAS locus on chromosome 14 in schizophrenia and healthy subjects
por: Alfimova, Margarita, et al.
Publicado: (2020) -
A comparison of taxon-like schizotypal clusters of non-clinical individuals on polygenic scores for schizophrenia and related phenotypes
por: Alfimova, M., et al.
Publicado: (2023) -
The impact of the oxytocin receptor gene (OXTR) on facial affect recognition in psychosis
por: Mikhailova, V., et al.
Publicado: (2022) -
The effects of fetal or neonatal hypoxia and genetic variants on age at onset of schizophrenia
por: Golimbet, V., et al.
Publicado: (2022)