Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesia

Levodopa is the most effective therapy for the motor deficits of Parkinson's disease (PD), but long term treatment leads to the development of L-DOPA-induced dyskinesia (LID). Our previous studies indicate enhanced excitability of striatal cholinergic interneurons (ChIs) in mice expressing LID...

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Detalles Bibliográficos
Autores principales: Lim, Sean Austin O., Xia, Rong, Ding, Yunmin, Won, Lisa, Ray, William J., Hitchcock, Stephen A., McGehee, Daniel S., Kang, Un Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563247/
https://www.ncbi.nlm.nih.gov/pubmed/25661301
http://dx.doi.org/10.1016/j.nbd.2015.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563247/
https://www.ncbi.nlm.nih.gov/pubmed/25661301
http://dx.doi.org/10.1016/j.nbd.2015.01.003

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