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Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesia
Levodopa is the most effective therapy for the motor deficits of Parkinson's disease (PD), but long term treatment leads to the development of L-DOPA-induced dyskinesia (LID). Our previous studies indicate enhanced excitability of striatal cholinergic interneurons (ChIs) in mice expressing LID...
Autores principales: | Lim, Sean Austin O., Xia, Rong, Ding, Yunmin, Won, Lisa, Ray, William J., Hitchcock, Stephen A., McGehee, Daniel S., Kang, Un Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563247/ https://www.ncbi.nlm.nih.gov/pubmed/25661301 http://dx.doi.org/10.1016/j.nbd.2015.01.003 |
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