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In Vivo MRI-CEST Tumor pH Imaging Detects Resistance to Proton Pump Inhibitors in Human Prostate Cancer Murine Models

SIMPLE SUMMARY: Tumor acidosis plays a major role in tumor aggressiveness, invasion and resistance, and it is considered an important target for novel anticancer strategies. In this work, we investigated the therapeutic efficacy of several proton pump inhibitors (Esomeprazole, Lansoprazole, Amilorid...

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Detalles Bibliográficos
Autores principales: Irrera, Pietro, Consolino, Lorena, Roberto, Miriam, Capozza, Martina, Dhakan, Chetan, Carella, Antonella, Corrado, Alessia, Villano, Daisy, Anemone, Annasofia, Navarro-Tableros, Victor, Bracesco, Martina, Dastrù, Walter, Aime, Silvio, Longo, Dario Livio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563279/
https://www.ncbi.nlm.nih.gov/pubmed/36230838
http://dx.doi.org/10.3390/cancers14194916