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Pyrotinib Targeted EGFR-STAT3/CD24 Loop-Mediated Cell Viability in TSC

Pyrotinib is an irreversible pan-ErbB receptor tyrosine kinase inhibitor, designed for the therapy of HER2-positive breast cancers. Inhibition of the epidermal growth factor receptor (EGFR, HER family) efficiently and selectively suppresses the proliferation of human TSC2-deficient smooth muscle cel...

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Detalles Bibliográficos
Autores principales: Han, Xiao, Zhang, Yupeng, Li, Yin, Lin, Zhoujun, Pei, Xiaolin, Feng, Ya, Yang, Juan, Li, Fei, Li, Tianjiao, Fu, Zhenkun, Wang, Changjun, Li, Chenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563285/
https://www.ncbi.nlm.nih.gov/pubmed/36231025
http://dx.doi.org/10.3390/cells11193064