Obligatory Role of AMPK Activation and Antioxidant Defense Pathway in the Regulatory Effects of Metformin on Cellular Protection and Prevention of Lens Opacity

Increasing levels of oxidative-stress due to deterioration of the Nrf2 (NFE2-related factor)/ARE (antioxidant response element) pathway is found to be a primary cause of aging pathobiology. Metformin having anti-aging effects can delay/halt aging-related diseases. Herein, using lens epithelial cell...

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Detalles Bibliográficos
Autores principales: Chhunchha, Bhavana, Kubo, Eri, Singh, Dhirendra P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563310/
https://www.ncbi.nlm.nih.gov/pubmed/36230981
http://dx.doi.org/10.3390/cells11193021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563310/
https://www.ncbi.nlm.nih.gov/pubmed/36230981
http://dx.doi.org/10.3390/cells11193021

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