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The human myocardium harbors a population of naive B-cells with a distinctive gene expression signature conserved across species

INTRODUCTION: Cardiac immunology studies in murine models have identified a sizeable population of myocardial B-cells and have shown that its modulation represents a promising strategy to develop novel therapies for heart failure. However, scarce data on B-cells in the human heart leaves unclear whe...

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Detalles Bibliográficos
Autores principales: Bermea, Kevin C., Kostelecky, Nicolas, Rousseau, Sylvie T., Lin, Chieh-Yu, Adamo, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563334/
https://www.ncbi.nlm.nih.gov/pubmed/36248879
http://dx.doi.org/10.3389/fimmu.2022.973211