The Nicotinic Receptor Polymorphism rs16969968 Is Associated with Airway Remodeling and Inflammatory Dysregulation in COPD Patients

Genome-wide association studies unveiled the associations between the single nucleotide polymorphism rs16969968 of CHRNA5, encoding the nicotinic acetylcholine receptor alpha5 subunit (α5SNP), and nicotine addiction, cancer, and COPD independently. Here, we investigated α5SNP-induced epithelial remo...

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Detalles Bibliográficos
Autores principales: Saber Cherif, Lynda, Diabasana, Zania, Perotin, Jeanne-Marie, Ancel, Julien, Petit, Laure M. G., Devilliers, Maëva A., Bonnomet, Arnaud, Lalun, Nathalie, Delepine, Gonzague, Maskos, Uwe, Gosset, Philippe, Polette, Myriam, Muggeo, Anaëlle, Guillard, Thomas, Deslée, Gaëtan, Dormoy, Valérian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563397/
https://www.ncbi.nlm.nih.gov/pubmed/36230899
http://dx.doi.org/10.3390/cells11192937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563397/
https://www.ncbi.nlm.nih.gov/pubmed/36230899
http://dx.doi.org/10.3390/cells11192937

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