Interplay of the transcription factor MRTF-A and matrix stiffness controls mammary acinar structure and protrusion formation

BACKGROUND: Ongoing differentiation processes characterize the mammary gland during sexual development and reproduction. In contrast, defective remodelling is assumed to be causal for breast tumorigenesis. We have shown recently that the myocardin-related transcription factor A (MRTF-A) is essential...

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Detalles Bibliográficos
Autores principales: Melcher, Marie-Luise, Block, Ines, Kropf, Karolin, Singh, Anurag Kumar, Posern, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563482/
https://www.ncbi.nlm.nih.gov/pubmed/36229824
http://dx.doi.org/10.1186/s12964-022-00977-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563482/
https://www.ncbi.nlm.nih.gov/pubmed/36229824
http://dx.doi.org/10.1186/s12964-022-00977-2

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