PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages

BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is the ninth member of the proprotein convertase family that regulates lipoprotein homeostasis and altered PCSK9 expression was reportedly associated with tumor development and progression. This study assessed PCSK9 expression and fun...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Li, Shuangshuang, Luo, Huanhua, Lu, Qi, Yu, Shuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563506/
https://www.ncbi.nlm.nih.gov/pubmed/36242053
http://dx.doi.org/10.1186/s13046-022-02477-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563506/
https://www.ncbi.nlm.nih.gov/pubmed/36242053
http://dx.doi.org/10.1186/s13046-022-02477-0

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