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Post-Translational Modifications of cGAS-STING: A Critical Switch for Immune Regulation

Innate immune mechanisms initiate immune responses via pattern-recognition receptors (PRRs). Cyclic GMP-AMP synthase (cGAS), a member of the PRRs, senses diverse pathogenic or endogenous DNA and activates innate immune signaling pathways, including the expression of stimulator of interferon genes (S...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Liu, Jingyang, Liu, Cun, Liu, Ruijuan, Liu, Lijuan, Yu, Zhenhai, Zhuang, Jing, Sun, Changgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563579/
https://www.ncbi.nlm.nih.gov/pubmed/36231006
http://dx.doi.org/10.3390/cells11193043