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Single-cell mutation calling and phylogenetic tree reconstruction with loss and recurrence
MOTIVATION: Tumours evolve as heterogeneous populations of cells, which may be distinguished by different genomic aberrations. The resulting intra-tumour heterogeneity plays an important role in cancer patient relapse and treatment failure, so that obtaining a clear understanding of each patient’s t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563700/ https://www.ncbi.nlm.nih.gov/pubmed/36000873 http://dx.doi.org/10.1093/bioinformatics/btac577 |