Preliminary Development and Testing of C595 Radioimmunoconjugates for Targeting MUC1 Cancer Epitopes in Pancreatic Ductal Adenocarcinoma

Mucin 1 is a transmembrane glycoprotein which overexpresses cancer-specific epitopes (MUC1-CE) on pancreatic ductal adenocarcinoma (PDAC) cells. As PDAC is a low survival and highly aggressive malignancy, developing radioimmunoconjugates capable of targeting MUC1-CE could lead to improvements in PDA...

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Detalles Bibliográficos
Autores principales: Hull, Ashleigh, Li, Yanrui, Bartholomeusz, Dylan, Hsieh, William, Tieu, William, Pukala, Tara L., Staudacher, Alexander H., Bezak, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563759/
https://www.ncbi.nlm.nih.gov/pubmed/36230945
http://dx.doi.org/10.3390/cells11192983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563759/
https://www.ncbi.nlm.nih.gov/pubmed/36230945
http://dx.doi.org/10.3390/cells11192983

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