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Supraphysiological Oxygen Levels in Mammalian Cell Culture: Current State and Future Perspectives

Most conventional incubators used in cell culture do not regulate O(2) levels, making the headspace O(2) concentration ~18%. In contrast, most human tissues are exposed to 2–6% O(2) (physioxia) in vivo. Accumulating evidence has shown that such hyperoxic conditions in standard cell culture practices...

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Detalles Bibliográficos
Autores principales: Alva, Ricardo, Gardner, Georgina L., Liang, Ping, Stuart, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563760/
https://www.ncbi.nlm.nih.gov/pubmed/36231085
http://dx.doi.org/10.3390/cells11193123