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A Ca(2+)-Mediated Switch of Epiplakin from a Diffuse to Keratin-Bound State Affects Keratin Dynamics

Keratins exert important structural but also cytoprotective functions. They have to be adaptable to support cellular homeostasis. Epiplakin (EPPK1) has been shown to decorate keratin filaments in epithelial cells and to play a protective role under stress, but the mechanism is still unclear. Using l...

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Detalles Bibliográficos
Autores principales: Ratajczyk, Sonia, Drexler, Corinne, Windoffer, Reinhard, Leube, Rudolf E., Fuchs, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563781/
https://www.ncbi.nlm.nih.gov/pubmed/36231039
http://dx.doi.org/10.3390/cells11193077