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Loss of Homeostatic Microglia Signature in Prion Diseases

Prion diseases are neurodegenerative diseases that affect humans and animals. They are always fatal and, to date, no treatment exists. The hallmark of prion disease pathophysiology is the misfolding of an endogenous protein, the cellular prion protein (PrP(C)), into its disease-associated isoform Pr...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Hartmann, Kristin, Thies, Edda, Mohammadi, Behnam, Altmeppen, Hermann, Sepulveda-Falla, Diego, Glatzel, Markus, Krasemann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563810/
https://www.ncbi.nlm.nih.gov/pubmed/36230910
http://dx.doi.org/10.3390/cells11192948