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Loss of Homeostatic Microglia Signature in Prion Diseases
Prion diseases are neurodegenerative diseases that affect humans and animals. They are always fatal and, to date, no treatment exists. The hallmark of prion disease pathophysiology is the misfolding of an endogenous protein, the cellular prion protein (PrP(C)), into its disease-associated isoform Pr...
Autores principales: | Wang, Yue, Hartmann, Kristin, Thies, Edda, Mohammadi, Behnam, Altmeppen, Hermann, Sepulveda-Falla, Diego, Glatzel, Markus, Krasemann, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563810/ https://www.ncbi.nlm.nih.gov/pubmed/36230910 http://dx.doi.org/10.3390/cells11192948 |
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