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[(18)F]NOS PET Brain Imaging Suggests Elevated Neuroinflammation in Idiopathic Parkinson’s Disease

Neuroinflammation is implicated as a key pathologic mechanism in many neurodegenerative diseases and is thought to be mediated in large part by microglia, native phagocytic immune cells of the CNS. Abnormal aggregation of the protein α-synuclein after phagocytosis by microglia is one possible neurop...

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Detalles Bibliográficos
Autores principales: Doot, Robert K., Young, Anthony J., Nasrallah, Ilya M., Wetherill, Reagan R., Siderowf, Andrew, Mach, Robert H., Dubroff, Jacob G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563966/
https://www.ncbi.nlm.nih.gov/pubmed/36231041
http://dx.doi.org/10.3390/cells11193081