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Genotyping of canine MHC gene DLA‐88 by next‐generation sequencing reveals high frequencies of new allele discovery and gene duplication

Dogs have served as one of the most reliable preclinical models for a variety of diseases and treatments, including stem/progenitor cell transplantation. At the genetic epicenter of dog transplantation models, polymorphic major histocompatibility complex (MHC) genes are most impactful on transplanta...

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Detalles Bibliográficos
Autores principales: Pyo, Chul‐Woo, Harkey, Michael A., Torok‐Storb, Beverly, Storb, Rainer, Wang, Ruihan, Thomas, Alexander S., Nelson, Wyatt C., Geraghty, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9563979/
https://www.ncbi.nlm.nih.gov/pubmed/36227705
http://dx.doi.org/10.1111/tan.14752