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The RNA-Binding Landscape of HAX1 Protein Indicates Its Involvement in Translation and Ribosome Assembly

HAX1 is a human protein with no known homologues or structural domains. Mutations in the HAX1 gene cause severe congenital neutropenia through mechanisms that are poorly understood. Previous studies reported the RNA-binding capacity of HAX1, but the role of this binding in physiology and pathology r...

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Detalles Bibliográficos
Autores principales: Balcerak, Anna, Macech-Klicka, Ewelina, Wakula, Maciej, Tomecki, Rafal, Goryca, Krzysztof, Rydzanicz, Malgorzata, Chmielarczyk, Mateusz, Szostakowska-Rodzos, Malgorzata, Wisniewska, Marta, Lyczek, Filip, Helwak, Aleksandra, Tollervey, David, Kudla, Grzegorz, Grzybowska, Ewa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564044/
https://www.ncbi.nlm.nih.gov/pubmed/36230905
http://dx.doi.org/10.3390/cells11192943