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The Drivers, Mechanisms, and Consequences of Genome Instability in HPV-Driven Cancers
SIMPLE SUMMARY: Cells infected with high-risk human papillomaviruses (HPV) can accumulate DNA damage and eventually transform into HPV-driven cancers. Genome instability, or the progressive accumulation of DNA alterations (e.g., mutations), in HPV-infected cells is directly induced by the HPV genes...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564061/ https://www.ncbi.nlm.nih.gov/pubmed/36230545 http://dx.doi.org/10.3390/cancers14194623 |