The Drivers, Mechanisms, and Consequences of Genome Instability in HPV-Driven Cancers

SIMPLE SUMMARY: Cells infected with high-risk human papillomaviruses (HPV) can accumulate DNA damage and eventually transform into HPV-driven cancers. Genome instability, or the progressive accumulation of DNA alterations (e.g., mutations), in HPV-infected cells is directly induced by the HPV genes...

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Detalles Bibliográficos
Autores principales: Porter, Vanessa L., Marra, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564061/
https://www.ncbi.nlm.nih.gov/pubmed/36230545
http://dx.doi.org/10.3390/cancers14194623

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