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Sphingosine 1-phosphate receptor 2 mediated early stages of pancreatic and systemic inflammatory responses via NF-kappa B activation in acute pancreatitis

In acute pancreatitis, activation of inflammatory signaling, including the nuclear factor-kappa B (NF-κB) pathway, within acinar cells is known to be an early intracellular event occurring in parallel with pathologic trypsinogen activation. Sphingosine 1-phosphate receptor 2 (S1PR2) plays a critical...

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Detalles Bibliográficos
Autores principales: Yang, Jing, Tang, Xujiao, Li, Baiqiang, Shi, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564071/
https://www.ncbi.nlm.nih.gov/pubmed/36229875
http://dx.doi.org/10.1186/s12964-022-00971-8