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Immunomodulatory Effect and Bone Homeostasis Regulation in Osteoblasts Differentiated from hADMSCs via the PD-1/PD-L1 Axis

Human mesenchymal stem cells (hMSCs) are promising candidates for stem cell therapy and are known to secrete programmed death-1 (PD-1) ligand 1 (PD-L1) regulating T cell-mediated immunosuppression. Given the limitations of current stem cell therapy approaches, improvements in immunomodulatory capaci...

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Detalles Bibliográficos
Autores principales: Lee, Seung-Cheol, Shin, Min Kyoung, Jang, Bo-Young, Lee, Seung-Ho, Kim, Min, Sung, Jung-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564087/
https://www.ncbi.nlm.nih.gov/pubmed/36231113
http://dx.doi.org/10.3390/cells11193152