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The Clonal Diversity of Peripheral B Cell Receptor Immune Repertoire Impaired by Residual Malignant B Cells Predicts Treatment Efficacy in B Cell Lymphoma Patients

SIMPLE SUMMARY: This study, for the first time, provided both in-vitro and clinical evidence that established a connection between the presence of residual malignant B cells and the clonal diversity of the resulting BCR repertoire. Lymphoma cells cultured with human germinal center B cells suppresse...

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Detalles Bibliográficos
Autores principales: Wu, Meng, Zhang, Jing, Wang, Yi, Mi, Lan, Wang, Xiaopei, Liu, Weiping, Fu, Jie, Song, Haifeng, Song, Yuqin, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564088/
https://www.ncbi.nlm.nih.gov/pubmed/36230551
http://dx.doi.org/10.3390/cancers14194628